The 335 is most likely worth it. For me the sheer work with replacing pickups and wring harness is enough, to avoid it.
Les Paul and Telecaster through an old school single channel tube amp are my preferred tools for blues and classic rock.
That Hendrix guy could offer a bit of blues and he used one of them new-fangled Stratoblaster things ... before you know it all the kids'll want one (I'm looking at you Eric and Rory ... not YOU Paul!).
I have both, and they both work fine. The 335 is cleaner and brighter. The Les Pauls are thicker and go into distortion sooner. Once you gain them up there isn't that much difference though. The pickups sound different, but that isn't about the guitar, that's about the difference between pickups. Find the guitar you like best, and use that. I can't make up my mind, so I use all of them!
Would you say that the 335 has a broader sonic palate compared with a Les Paul ?
I dont know what you guys think but I tend to think that it does, as the LPs maple top tends to focus and emphasise certain midrange frequencies and harmonics that make the LP model a legend, but not for its huge versatility..
However the all mahogany Les Paul Custom has this beautifully even tone response, right across the spectrum and as such may offer a viable alternative for the guitarist that loves the tone of the es335 but is more comfortable with the LP body shape.