2x12 cab wiring?

[SlyStrat]

I need a 2x12 cab for my Marshall 2061X. The amp has taps for 16, 8, and 4 ohms.
Which will sound best and why?
2- 8 ohm speakers wired in series for 16 ohm load
2- 16 ohm speakers wired in parallel for 8 ohm load

 

[Loko]

These are the stats on the cab that is designed for that head.

60-watt, 8-ohm, mono, 2x12" cabinet with angled front
• Designed to partner the Handwired 2061X 20-watt head
• Loaded with two 30 Watt, Celestion G12H reissue speakers
• "Salt and Pepper" (a.k.a. Grey Basket Weave) grille cloth
• Metal Handles
• High-grade, Baltic birch cabinet with finger-locked joints