I have the line out on my computer going to one of the line inputs on an old stereo receiver connected to a pair of big old floor speakers. Whatever audio I play on the computer whether mp3, youtube, etc. goes through that. Guitar goes into pedal board / guitar amp.
I bought a 5:25+ shortly after they came out and did some research on the difference between the original and +. From what I remember there were 3 major differences:
1. The clean channel circuit was changed to be similar to the Lone Star Special clean which many viewed as an improvement.