About time! Sticky this thread! Way valuable post for me since I came here. When I chanced about Splat's tip, I was having a hard time dialing in a tone that can go from raunch dirty to pristinely clean at the touch of the knobs. It didn't occur to me how valuable the tone knob is. I thought it was just something to cut the treble.
So the way I approach les paul controls now is, EQ for the neck, roll back the bridge tone. Then I adjust the amp gain so that it's dirty on 10, but I get clean clean tone, even when I dig in, around 2-3 of the bridge volume knob.
This way, I can easily switch from clean to crunch at the turn of the volume knob. Then use the tone knob for more cut if playing with other instruments. Step on an overdrive pedal set to boost for heavier music. With the bridge set to clean, I can further thin out the les paul bridge honk by switching to the middle position, utilizing phase cancellation to my advantage for those funky rhythm comps.
Thanks again Splat.